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Fig. 6 | BMC Systems Biology

Fig. 6

From: Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes

Fig. 6

Heatmaps show the overall liver mass recovered is sensitive to combinatorial effects of a Metabolic load and hepatocyte growth rate, b IL-6 turnover rate, and c GF turnover rate. All parameter changes are displayed in Fold change [FC] over nominal parameter value. a The proper balance between regenerative drive and cell growth in response to stress is required for normal regeneration. b IL-6 and c GF production rates have large-scale effects on overall recovery, while degradation rates act as fine tuning

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BMC Systems Biology

ISSN: 1752-0509

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