Table 2 Descriptions for the model parameters
Parameter | Description |
|---|---|
θ 1 | conversion rate for IL6 |
θ 2 | basal expression, STAT3 |
θ 3 | autoregulation, STAT3 |
θ 4 | mRNA degradation, STAT3 |
θ 5 | translation, STAT3 |
θ 6 | phosphorylation, STAT3 |
θ 7 | protein degradation, STAT3 |
θ 8 | phosphoprotein degradation, STAT3 |
θ 9 | conversion rate for TGF β |
θ 10 | ROR γt activation by TGF β and STAT3 |
θ 11 | ROR γt inhibition by FOXP3 |
θ 12 | ROR γt degradation |
θ 13 | basal expression, FOXP3 |
θ 14 | FOXP3 activation by TGF β |
θ 15 | FOXP3 inhibition by STAT3 |
θ 16 | mRNA degradation, FOXP3 |
θ 17 | translation/phosphorylation, FOXP3 |
θ 18 | protein degradation, FOXP3 |