Fig. 4

Workflow and summary of RNA editing events observed in naïve CD4+ T cells. a The workflow that was used to identify putative sites of RNA editing in naïve CD4+ T cell transcriptome. The number of putative RNA editing sites is shown on the y-axis and reasons for disqualifying them are represented on the x-axis. b Matrix showing all the nucleotide substitutions observed in the confirmed RNA editing sites. The numbers highlighted in red indicate canonical changes (A-to-G and C-to-T). G-to-A and T-to-C are also highlighted as those changes are likely canonical edits with incorrect strand assignment of RNA-Seq data. Numbers highlighted in green are non-canonical events. c Distribution of RNA editing sites based on their location within transcripts