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Fig. 7 | BMC Systems Biology

Fig. 7

From: Integrating transcriptional and protein interaction networks to prioritize condition-specific master regulators

Fig. 7

Rapamycin drivers with high combined network score interact with proteins enriched for nucleosome assembly and respiration. Heatmap shows the ranks of all rapamycin driver TFs according to either the transcriptional network degree, the protein interaction degree, or the combined network score, with red depicting higher ranks and blue depicting lower ranks. Network diagram shows all direct protein interactors of the rapamycin driver TFs that had a higher rank in the combined network score than in either individual network alone. Edges represent evidence of direct protein interaction from yeast two-hybrid experiments

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