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Fig. 9 | BMC Systems Biology

Fig. 9

From: Tracing regulatory routes in metabolism using generalised supply-demand analysis

Fig. 9

Rate characteristic plots of the reaction blocks of aspartate-semialdehyde in the aspartate metabolism model. a The fluxes of the demand blocks 6, 7, 14 and 15, and the supply block 5 of ASA. b The rate characteristic plot of the ASA-supply block 5 with partial and total response coefficients indicated as lines intersecting the J 5-curve at the steady-state value of ASA. Partial response coefficients (solid lines) indicate the relative contribution of each respective route of interaction of ASA with block 5 towards the total response coefficient (dashed line). The unlabelled dashed curve in both (a) and (b) represents the total demand and the steady-state value of ASA is indicated as a vertical dotted line (see Table 2)

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