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Table 1 Abundance and activity values for CYP subfamilies after normalization

From: PROXIMAL: a method for Prediction of Xenobiotic Metabolism

CYP Abundance Activity
Average min max Average min max
1A2 0.0895 0.0089 0.1232 0.0414 0.0000 0.0773
2A6 0.1245 0.0906 0.1888 0.1393 0.1189 0.1664
2B6 0.0177 0.0000 0.0906 0.0814 0.0450 0.0976
2C8 0.1003 0.0906 0.1232 0.1441 0.0976 0.1664
2C9 0.2226 0.1888 0.2498 0.1198 0.0000 0.1541
2C19 0.0114 0.0000 0.0154 0.0580 0.0000 0.1541
2D6 0.0069 0.0000 0.0154 0.0985 0.0450 0.1664
2E1 0.1898 0.0994 0.2498 0.1669 0.1389 0.2018
3A4 0.2374 0.1888 0.2498 0.1506 0.0000 0.2018
  1. Columns 2, 3 and 4 represent the normalized average, minimum and maximum CYP abundance values estimated from experimental data across multiple studies [38, 39, 4143]. Columns 5, 6, and 7 represent the normalized average, minimum and maximum CYP activities estimated from experimental data across multiple studies [4448]