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Table 1 Abundance and activity values for CYP subfamilies after normalization

From: PROXIMAL: a method for Prediction of Xenobiotic Metabolism

CYP

Abundance

Activity

Average

min

max

Average

min

max

1A2

0.0895

0.0089

0.1232

0.0414

0.0000

0.0773

2A6

0.1245

0.0906

0.1888

0.1393

0.1189

0.1664

2B6

0.0177

0.0000

0.0906

0.0814

0.0450

0.0976

2C8

0.1003

0.0906

0.1232

0.1441

0.0976

0.1664

2C9

0.2226

0.1888

0.2498

0.1198

0.0000

0.1541

2C19

0.0114

0.0000

0.0154

0.0580

0.0000

0.1541

2D6

0.0069

0.0000

0.0154

0.0985

0.0450

0.1664

2E1

0.1898

0.0994

0.2498

0.1669

0.1389

0.2018

3A4

0.2374

0.1888

0.2498

0.1506

0.0000

0.2018

  1. Columns 2, 3 and 4 represent the normalized average, minimum and maximum CYP abundance values estimated from experimental data across multiple studies [38, 39, 41–43]. Columns 5, 6, and 7 represent the normalized average, minimum and maximum CYP activities estimated from experimental data across multiple studies [44–48]
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BMC Systems Biology

ISSN: 1752-0509

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