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Table 1 New associated pathways and SNPs under ethanol condition

From: A network based covariance test for detecting multivariate eQTL in saccharomyces cerevisiae

Pathways Associated markers
Glycolysis/Gluconeogenesis g O L02(10)
Synthesis and degradation of ketone bodies Y L R257W (10),Y L R261C (10)
Steroid biosynthesis Y E L021W L , Y F R035C L ,
  Y J L001W L , Y J R006W L,(10),
  Y J L007C L,(10),
Valine, leucine and isoleucine degradation Y O R006C L , N O R005W L,(10),
  Y O R051C L,(10), Y O R076C L,(10)
Valine, leucine and isoleucine N L R116W L,(10), Y O R076C L ,
biosynthesis Y C L023C (10), Y L R257W (10)
Histidine metabolism g O L02L,(10), Y O R025W (10)
Tyrosine metabolism Y F L019C L , g O L02L,(10)
Phenylalanine metabolism g O L02L,(10)
beta-Alanine metabolism g O L02L,(10)
Taurine and hypotaurine metabolism g O L02(10)
Selenocompound metabolism Y O R006C L,(10), Y O R019W L,(10),
  Y O R025W L,(10), N O R005W L,(10)
Purine metabolism N N L035W (1)
Cyanoamino acid metabolism Y L R027C (1)
Arachidonic acid metabolism g P L09(1)
Linoleic acid metabolism Y F L029C L,(1),(10), Y F L019C (1)
Glyoxylate and dicarboxylate metabolism N N L035W (1), Y N L074C (1)
Porphyrin and chlorophyll metabolism N B R008W (1)
Sphingolipid metabolism Y H L047C L
Pantothenate and CoA biosynthesis Y G L053W L , N L R116W L,(10)
Terpenoid backbone biosynthesis Y J L007C L,(10), Y J L001W L,(10),
  Y J R006W L,(10), N J R006C L,(10)
Sesquiterpenoid and triterpenoid Y O R334W L , Y O R343C L ,
  Y L R261C (10), N L R116W (10),
  Y L R257W (10)
Metabolic pathways Y I L078W (10), Y L R257W (10),
  Y L R308W (10), N N L035W (10),
  g O L02(10), Y O R006C (10),
  Y O R051C (10),Y O R019W (10),
  Y N L066W (10),Y L R261C (10)
Biosynthesis of secondary metabolites Y O R025W (10), Y O R063W (10)
Carbon metabolism Y O R019W (10)
2-Oxocarboxylic acid metabolism Y L R261C L,(10), Y L R308W L,(10),
  Y C L022C (10), Y L R265C (10),
  N L R116W (10),Y L R322W L
mRNA surveillance pathway Y O R072W L
Mismatch repair g K R08L
Non-homologous end Y G R006W L
Biosynthesis of amino acids g O L02(10)
MAPK signaling pathway Y D R164C (10), g D R10(10)
  1. L means detected by covariance test, (1) means detected by kernel covariance test with parameter 1 and (10) means detected by kernel covariance test with parameter 10. The FDR of the covariance test, kernel covariance test with parameter 1 and kernel covariance test with parameter 10 are 0.25, 0.33 and 0.25 respectively. The FWER of the test by Tony Cai is 0.2