Table 2 Performance evaluation of the investigated features in identifying ubiquitylation sites based on five-fold cross-validation
| Investigated features | Sensitivity | Specificity | Accuracy | MCC |
|---|---|---|---|---|
| 20D binary coding (20D) | 65.59 % | 67.09 % | 66.64 % | 0.303 |
| Amino Acid Composition (AAC) | 64.34 % | 65.44 % | 65.11 % | 0.275 |
| Amino Acid Pair Composition (AAPC) | 68.70 % | 70.72 % | 70.11 % | 0.367 |
| Position Weight Matrix (PWM) | 68.08 % | 67.99 % | 68.01 % | 0.334 |
| Position-Specific Scoring Matrix (PSSM) | 69.46 % | 70.69 % | 70.32 % | 0.374 |
| Solvent-Accessible Surface Area (SASA) | 64.58 % | 65.47 % | 65.20 % | 0.278 |
| Secondary Structure (SS) | 55.20 % | 60.51 % | 58.91 % | 0.145 |