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Table 3 Inputs of the simulation in section “Model comparison and validation with real data”

From: Generalized logical model based on network topology to capture the dynamical trends of cellular signaling pathways

  EGFR TNFR DNA damage
Control +0.5 +0.5 random value
EGFR inhibitor –1 +0.5 random value
DNA damage stimuli random value +0.5 +1
Both drugs –1 +0.5 +1
  1. The symbols ‘+’ and ‘–’ represent the perturbation types, i.e., activation and inhibition. The columns are the input nodes of simulation and the rows are various conditions including the treatments of biological experiments with drugs corresponding to wet-lab experiments in [18]