Fig. 3From: Scope and limitations of yeast as a model organism for studying human tissue-specific pathwaysAlignment graph of core human genes. Conserved edges in the alignment graph of core housekeeping genes, which correspond to the “interologs,” i.e. orthologous pairs of interacting proteins between yeast and human. Five main protein clusters, identified as dense regions of interaction in the alignment graph, are marked accordingly and annotated with their dominant functional annotation as follows: a Ribosome, b Processing of capped intron-containing pre-mRNA, c Proteasome, d vATPase, e Cap-dependent translation initiationBack to article page