Fig. 6
From: Scope and limitations of yeast as a model organism for studying human tissue-specific pathways
Distribution of tissue-selectivity p-values in different tissue groups. a Brain tissues, b Blood cells, c Ganglion tissues, d Testis tissues. Each plot resembles the same bi-modal distribution as the gene-tissue membership density, with blood cells and brain tissues presenting the most clear separation of tissue-selective genes. The critical points of each distribution function, where the derivative of pdf function is approximately zero, is marked on each plot. These points provide optimal cutoff points for the tissue-selectivity p-values as they mark the points of shift in the underlying distribution function