Fig. 9
Spatial profiles obtained at the end of 1000 h dynamic simulations for three scenarios: no O2 supplied at the tissue-biofilm interface and succinate consumption not allowed (“Nominal”); O2 supplied at the tissue-biofilm interface by imposing a mass transfer limited boundary condition with a plasma O2 concentration of 0.05 mmol/L but succinate consumption not allowed (“O2 Tissue”); and O2 supplied at the tissue-biofilm interface and succinate consumption introduced assuming the same uptake kinetic parameters as used for glucose