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Fig. 6 | BMC Systems Biology

Fig. 6

From: Feedback control in planarian stem cell systems

Fig. 6

Cell dynamics during remodeling following a division. We assume that the initial cell numbers are 50 % of the steady state number of neoblasts, and 10 %, 30 %, and 5 % of the steady state values of the three kinds of differentiated cells respectively (rather than 25 % neoblasts and 40 %, 30 %, 30 % relative distribution of differentiated cells in the steady state). Starting from relatively small size, the planarian grows to a steady state, since food is constant) (first panel), experiences a burst of mortality initially (second panel) as the differentiated cells apoptose in order to achieve their target values (fourth panel; colors are red: ρ 2, black: ρ 1, and blue: ρ 3), and a complicated trajectory for the fraction of neoblasts as the animal readjusts its composition

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