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Fig. 4 | BMC Systems Biology

Fig. 4

From: Low potency toxins reveal dense interaction networks in metabolism

Fig. 4

UnBiological vs. toxicity for selected organisms. Plots of UnBiological vs. toxicity endpoints for three of the data sets analysed here. Each dot represents the LD50 (X axis) vs Ub value (Y axis) for one compound. Ub is calculated as described in the Methods section and Appendix 2. In summary, Ub represents the largest region on a molecule that is not present in a metabolite, as defined by a 5-atom (Ub 5 ) or 6-atom (Ub 6 ) overlap. a: Ub 5 vs. LD50 for Chlorella, b: Ub6 vs. LD50 for Rainbow trout, c: Ub 6 vs. LD50 for Lemna, intoxicated with compounds other than herbicides

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