TY - JOUR AU - Pollak, M. PY - 2008 DA - 2008// TI - Insulin and insulin-like growth factor signalling in neoplasia JO - Nat Rev Cancer VL - 8 UR - https://doi.org/10.1038/nrc2536 DO - 10.1038/nrc2536 ID - Pollak2008 ER - TY - JOUR AU - Brokaw, J. AU - Katsaros, D. AU - Wiley, A. AU - Lu, L. AU - Su, D. AU - Sochirca, O. PY - 2007 DA - 2007// TI - IGF-I in epithelial ovarian cancer and its role in disease progression JO - Growth Factors VL - 25 UR - https://doi.org/10.1080/08977190701838402 DO - 10.1080/08977190701838402 ID - Brokaw2007 ER - TY - JOUR AU - Sayer, R. A. AU - Lancaster, J. M. AU - Pittman, J. AU - Gray, J. AU - Whitaker, R. AU - Marks, J. R. PY - 2005 DA - 2005// TI - High insulin-like growth factor-2 (IGF-2) gene expression is an independent predictor of poor survival for patients with advanced stage serous epithelial ovarian cancer JO - Gynecol Oncol VL - 96 UR - https://doi.org/10.1016/j.ygyno.2004.10.012 DO - 10.1016/j.ygyno.2004.10.012 ID - Sayer2005 ER - TY - JOUR AU - Endogenous, H. AU - Key, T. J. AU - Appleby, P. N. AU - Reeves, G. K. AU - Roddam, A. W. PY - 2010 DA - 2010// TI - Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies JO - Lancet Oncol VL - 11 UR - https://doi.org/10.1016/S1470-2045(10)70095-4 DO - 10.1016/S1470-2045(10)70095-4 ID - Endogenous2010 ER - TY - JOUR AU - Abir, R. AU - Roizman, P. AU - Fisch, B. AU - Nitke, S. AU - Okon, E. AU - Orvieto, R. PY - 1999 DA - 1999// TI - Pilot study of isolated early human follicles cultured in collagen gels for 24 hours JO - Hum Reprod VL - 14 UR - https://doi.org/10.1093/humrep/14.5.1299 DO - 10.1093/humrep/14.5.1299 ID - Abir1999 ER - TY - JOUR AU - Denduluria, S. I. O. AU - Wang, Z. AU - Liao, Z. AU - Yan, Z. AU - Mohammed, M. AU - Ye, J. PY - 2015 DA - 2015// TI - Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance JO - Genes Dis VL - 2 UR - https://doi.org/10.1016/j.gendis.2014.10.004 DO - 10.1016/j.gendis.2014.10.004 ID - Denduluria2015 ER - TY - JOUR AU - Pollak, M. PY - 2012 DA - 2012// TI - The insulin and insulin-like growth factor receptor family in neoplasia: an update JO - Nat Rev Cancer VL - 12 ID - Pollak2012 ER - TY - JOUR AU - Bruchim, I. AU - Werner, H. PY - 2013 DA - 2013// TI - Targeting IGF-1 signaling pathways in gynecologic malignancies JO - Expert Opin Ther Targets VL - 17 UR - https://doi.org/10.1517/14728222.2013.749863 DO - 10.1517/14728222.2013.749863 ID - Bruchim2013 ER - TY - JOUR AU - DeChiara, T. M. AU - Efstratiadis, A. AU - Robertson, E. J. PY - 1990 DA - 1990// TI - A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting JO - Nature VL - 345 UR - https://doi.org/10.1038/345078a0 DO - 10.1038/345078a0 ID - DeChiara1990 ER - TY - JOUR AU - Powell-Braxton, L. AU - Hollingshead, P. AU - Giltinan, D. AU - Pitts-Meek, S. AU - Stewart, T. PY - 1993 DA - 1993// TI - Inactivation of the IGF-I gene in mice results in perinatal lethality JO - Ann N Y Acad Sci VL - 692 UR - https://doi.org/10.1111/j.1749-6632.1993.tb26240.x DO - 10.1111/j.1749-6632.1993.tb26240.x ID - Powell-Braxton1993 ER - TY - JOUR AU - Oka, Y. AU - Rozek, L. M. AU - Czech, M. P. PY - 1985 DA - 1985// TI - Direct demonstration of rapid insulin-like growth factor II Receptor internalization and recycling in rat adipocytes. Insulin stimulates 125I-insulin-like growth factor II degradation by modulating the IGF-II receptor recycling process JO - J Biol Chem VL - 260 ID - Oka1985 ER - TY - JOUR AU - Liu, J. P. AU - Baker, J. AU - Perkins, A. S. AU - Robertson, E. J. AU - Efstratiadis, A. PY - 1993 DA - 1993// TI - Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) JO - Cell VL - 75 ID - Liu1993 ER - TY - JOUR AU - Soos, M. A. AU - Whittaker, J. AU - Lammers, R. AU - Ullrich, A. AU - Siddle, K. PY - 1990 DA - 1990// TI - Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells JO - Biochem J VL - 270 UR - https://doi.org/10.1042/bj2700383 DO - 10.1042/bj2700383 ID - Soos1990 ER - TY - JOUR AU - Kornfeld, S. PY - 1992 DA - 1992// TI - Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors JO - Annu Rev Biochem VL - 61 UR - https://doi.org/10.1146/annurev.bi.61.070192.001515 DO - 10.1146/annurev.bi.61.070192.001515 ID - Kornfeld1992 ER - TY - JOUR AU - Lau, M. M. AU - Stewart, C. E. AU - Liu, Z. AU - Bhatt, H. AU - Rotwein, P. AU - Stewart, C. L. PY - 1994 DA - 1994// TI - Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality JO - Genes Dev VL - 8 UR - https://doi.org/10.1101/gad.8.24.2953 DO - 10.1101/gad.8.24.2953 ID - Lau1994 ER - TY - JOUR AU - Wang, Z. Q. AU - Fung, M. R. AU - Barlow, D. P. AU - Wagner, E. F. PY - 1994 DA - 1994// TI - Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene JO - Nature VL - 372 UR - https://doi.org/10.1038/372464a0 DO - 10.1038/372464a0 ID - Wang1994 ER - TY - JOUR AU - Baxter, R. C. PY - 2014 DA - 2014// TI - IGF binding proteins in cancer: mechanistic and clinical insights JO - Nat Rev Cancer VL - 14 UR - https://doi.org/10.1038/nrc3720 DO - 10.1038/nrc3720 ID - Baxter2014 ER - TY - JOUR AU - Sitar, T. AU - Popowicz, G. M. AU - Siwanowicz, I. AU - Huber, R. AU - Holak, T. A. PY - 2006 DA - 2006// TI - Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins JO - Proc Natl Acad Sci U S A VL - 103 UR - https://doi.org/10.1073/pnas.0605652103 DO - 10.1073/pnas.0605652103 ID - Sitar2006 ER - TY - JOUR AU - An, Y. AU - Cai, L. AU - Wang, Y. AU - Zhu, D. AU - Guan, Y. AU - Zheng, J. PY - 2009 DA - 2009// TI - Local expression of insulin-like growth factor-I, insulin-like growth factor-I receptor, and estrogen receptor alpha in ovarian cancer JO - Onkologie VL - 32 UR - https://doi.org/10.1159/000242253 DO - 10.1159/000242253 ID - An2009 ER - TY - JOUR AU - Katsaros, D. AU - Yu, H. AU - Levesque, M. A. AU - Danese, S. AU - Genta, F. AU - Richiardi, G. PY - 2001 DA - 2001// TI - IGFBP-3 in epithelial ovarian carcinoma and its association with clinico-pathological features and patient survival JO - Eur J Cancer VL - 37 UR - https://doi.org/10.1016/S0959-8049(00)00423-8 DO - 10.1016/S0959-8049(00)00423-8 ID - Katsaros2001 ER - TY - JOUR AU - Toretsky, J. A. AU - Helman, L. J. PY - 1996 DA - 1996// TI - Involvement of IGF-II in human cancer JO - J Endocrinol VL - 149 UR - https://doi.org/10.1677/joe.0.1490367 DO - 10.1677/joe.0.1490367 ID - Toretsky1996 ER - TY - JOUR AU - Yu, H. AU - Rohan, T. PY - 2000 DA - 2000// TI - Role of the insulin-like growth factor family in cancer development and progression JO - J Natl Cancer Inst VL - 92 UR - https://doi.org/10.1093/jnci/92.18.1472 DO - 10.1093/jnci/92.18.1472 ID - Yu2000 ER - TY - JOUR AU - Devi, G. R. AU - Sprenger, C. C. AU - Plymate, S. R. AU - Rosenfeld, R. G. PY - 2002 DA - 2002// TI - Insulin-like growth factor binding protein-3 induces early apoptosis in malignant prostate cancer cells and inhibits tumor formation in vivo JO - Prostate VL - 51 UR - https://doi.org/10.1002/pros.10068 DO - 10.1002/pros.10068 ID - Devi2002 ER - TY - JOUR AU - Prasasya, R. D. AU - Tian, D. AU - Kreeger, P. K. PY - 2011 DA - 2011// TI - Analysis of cancer signaling networks by systems biology to develop therapies JO - Semin Cancer Biol VL - 21 UR - https://doi.org/10.1016/j.semcancer.2011.04.001 DO - 10.1016/j.semcancer.2011.04.001 ID - Prasasya2011 ER - TY - JOUR AU - Romanelli, R. J. AU - LeBeau, A. P. AU - Fulmer, C. G. AU - Lazzarino, D. A. AU - Hochberg, A. AU - Wood, T. L. PY - 2007 DA - 2007// TI - Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M704309200 DO - 10.1074/jbc.M704309200 ID - Romanelli2007 ER - TY - JOUR AU - Iadevaia, S. AU - Lu, Y. AU - Morales, F. C. AU - Mills, G. B. AU - Ram, P. T. PY - 2010 DA - 2010// TI - Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-10-0460 DO - 10.1158/0008-5472.CAN-10-0460 ID - Iadevaia2010 ER - TY - JOUR AU - Tian, D. AU - Kreeger, P. K. PY - 2014 DA - 2014// TI - Analysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy JO - BMC Syst Biol VL - 8 UR - https://doi.org/10.1186/s12918-014-0098-y DO - 10.1186/s12918-014-0098-y ID - Tian2014 ER - TY - JOUR AU - Zhang, L. AU - Smith, D. W. AU - Gardiner, B. S. AU - Grodzinsky, A. J. PY - 2013 DA - 2013// TI - Modeling the insulin-like growth factor system in articular cartilage JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0066870 DO - 10.1371/journal.pone.0066870 ID - Zhang2013 ER - TY - JOUR AU - Chisalita, S. I. AU - Johansson, G. S. AU - Liefvendahl, E. AU - Back, K. AU - Arnqvist, H. J. PY - 2009 DA - 2009// TI - Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2 JO - J Mol Endocrinol VL - 43 UR - https://doi.org/10.1677/JME-09-0021 DO - 10.1677/JME-09-0021 ID - Chisalita2009 ER - TY - JOUR AU - Chao, W. AU - D’Amore, P. A. PY - 2008 DA - 2008// TI - IGF2: epigenetic regulation and role in development and disease JO - Cytokine Growth Factor Rev VL - 19 UR - https://doi.org/10.1016/j.cytogfr.2008.01.005 DO - 10.1016/j.cytogfr.2008.01.005 ID - Chao2008 ER - TY - JOUR AU - Chen, Z. AU - Ge, Y. AU - Landman, N. AU - Kang, J. X. PY - 2002 DA - 2002// TI - Decreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells JO - BMC Cancer VL - 2 UR - https://doi.org/10.1186/1471-2407-2-18 DO - 10.1186/1471-2407-2-18 ID - Chen2002 ER - TY - JOUR AU - Lee, J. S. AU - Weiss, J. AU - Martin, J. L. AU - Scott, C. D. PY - 2003 DA - 2003// TI - Increased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor in breast cancer cells alters tumorigenic properties in vitro and in vivo JO - Int J Cancer VL - 107 UR - https://doi.org/10.1002/ijc.11453 DO - 10.1002/ijc.11453 ID - Lee2003 ER - TY - JOUR AU - Li, J. AU - Lu, Y. AU - Akbani, R. AU - Ju, Z. AU - Roebuck, P. L. AU - Liu, W. PY - 2013 DA - 2013// TI - TCPA: a resource for cancer functional proteomics data JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2650 DO - 10.1038/nmeth.2650 ID - Li2013 ER - TY - JOUR AU - Polo, J. M. AU - Anderssen, E. AU - Walsh, R. M. AU - Schwarz, B. A. AU - Nefzger, C. M. AU - Lim, S. M. PY - 2012 DA - 2012// TI - A molecular roadmap of reprogramming somatic cells into iPS cells JO - Cell VL - 151 UR - https://doi.org/10.1016/j.cell.2012.11.039 DO - 10.1016/j.cell.2012.11.039 ID - Polo2012 ER - TY - JOUR AU - Peeters, P. H. AU - Lukanova, A. AU - Allen, N. AU - Berrino, F. AU - Key, T. AU - Dossus, L. PY - 2007 DA - 2007// TI - Serum IGF-I, its major binding protein (IGFBP-3) and epithelial ovarian cancer risk: the European Prospective Investigation into Cancer and Nutrition (EPIC) JO - Endocr Relat Cancer VL - 14 UR - https://doi.org/10.1677/erc.1.01264 DO - 10.1677/erc.1.01264 ID - Peeters2007 ER - TY - JOUR AU - Dunn, S. E. AU - Ehrlich, M. AU - Sharp, N. J. AU - Reiss, K. AU - Solomon, G. AU - Hawkins, R. PY - 1998 DA - 1998// TI - A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer JO - Cancer Res VL - 58 ID - Dunn1998 ER - TY - JOUR AU - Singh, P. AU - Dai, B. AU - Yallampalli, U. AU - Lu, X. AU - Schroy, P. C. PY - 1996 DA - 1996// TI - Proliferation and differentiation of a human colon cancer cell line (CaCo2) is associated with significant changes in the expression and secretion of insulin-like growth factor (IGF) IGF-II and IGF binding protein-4: role of IGF-II JO - Endocrinology VL - 137 ID - Singh1996 ER - TY - JOUR AU - Sue, S. R. AU - Chari, R. S. AU - Kong, F. M. AU - Mills, J. J. AU - Fine, R. L. AU - Jirtle, R. L. PY - 1995 DA - 1995// TI - Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcinoma JO - Ann Surg VL - 222 UR - https://doi.org/10.1097/00000658-199508000-00009 DO - 10.1097/00000658-199508000-00009 ID - Sue1995 ER - TY - JOUR AU - Souza, A. T. AU - Hankins, G. R. AU - Washington, M. K. AU - Orton, T. C. AU - Jirtle, R. L. PY - 1995 DA - 1995// TI - M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity JO - Nat Genet VL - 11 UR - https://doi.org/10.1038/ng1295-447 DO - 10.1038/ng1295-447 ID - Souza1995 ER - TY - JOUR AU - Singer, C. F. AU - Mogg, M. AU - Koestler, W. AU - Pacher, M. AU - Marton, E. AU - Kubista, E. PY - 2004 DA - 2004// TI - Insulin-like growth factor (IGF)-I and IGF-II serum concentrations in patients with benign and malignant breast lesions: free IGF-II is correlated with breast cancer size JO - Clin Cancer Res VL - 10 UR - https://doi.org/10.1158/1078-0432.CCR-03-0093 DO - 10.1158/1078-0432.CCR-03-0093 ID - Singer2004 ER - TY - JOUR AU - Espelund, U. AU - Cold, S. AU - Frystyk, J. AU - Orskov, H. AU - Flyvbjerg, A. PY - 2008 DA - 2008// TI - Elevated free IGF2 levels in localized, early-stage breast cancer in women JO - Eur J Endocrinol VL - 159 UR - https://doi.org/10.1530/EJE-08-0154 DO - 10.1530/EJE-08-0154 ID - Espelund2008 ER - TY - JOUR AU - Jones, J. I. AU - Clemmons, D. R. PY - 1995 DA - 1995// TI - Insulin-like growth factors and their binding proteins: biological actions JO - Endocr Rev VL - 16 ID - Jones1995 ER - TY - JOUR AU - Torng, P. L. AU - Lee, Y. C. AU - Huang, C. Y. AU - Ye, J. H. AU - Lin, Y. S. AU - Chu, Y. W. PY - 2008 DA - 2008// TI - Insulin-like growth factor binding protein-3 (IGFBP-3) acts as an invasion-metastasis suppressor in ovarian endometrioid carcinoma JO - Oncogene VL - 27 UR - https://doi.org/10.1038/sj.onc.1210864 DO - 10.1038/sj.onc.1210864 ID - Torng2008 ER - TY - JOUR AU - Kaulsay, K. K. AU - Ng, E. H. AU - Ji, C. Y. AU - Ho, G. H. AU - Aw, T. C. AU - Lee, K. O. PY - 1999 DA - 1999// TI - Serum IGF-binding protein-6 and prostate specific antigen in breast cancer JO - Eur J Endocrinol VL - 140 UR - https://doi.org/10.1530/eje.0.1400164 DO - 10.1530/eje.0.1400164 ID - Kaulsay1999 ER - TY - JOUR AU - Chard, T. PY - 1994 DA - 1994// TI - Insulin-like growth factors and their binding proteins in normal and abnormal human fetal growth JO - Growth Regul VL - 4 ID - Chard1994 ER - TY - JOUR AU - Pannier, E. M. AU - Irwin, J. C. AU - Giudice, L. C. PY - 1994 DA - 1994// TI - Insulin-like growth factor-binding proteins in the human fetus: tissue-specific protein secretion, immunologic characterization, and gene expression JO - Am J Obstet Gynecol VL - 171 UR - https://doi.org/10.1016/0002-9378(94)90092-2 DO - 10.1016/0002-9378(94)90092-2 ID - Pannier1994 ER - TY - JOUR AU - Martina, N. A. AU - Kim, E. AU - Chitkara, U. AU - Wathen, N. C. AU - Chard, T. AU - Giudice, L. C. PY - 1997 DA - 1997// TI - Gestational age-dependent expression of insulin-like growth factor-binding protein-1 (IGFBP-1) phosphoisoforms in human extraembryonic cavities, maternal serum, and decidua suggests decidua as the primary source of IGFBP-1 in these fluids during early pregnancy JO - J Clin Endocrinol Metab VL - 82 ID - Martina1997 ER - TY - JOUR AU - Byrd, J. C. AU - MacDonald, R. G. PY - 2000 DA - 2000// TI - Mechanisms for high affinity mannose 6-phosphate ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M000010200 DO - 10.1074/jbc.M000010200 ID - Byrd2000 ER - TY - JOUR AU - Buckley, D. A. AU - Loughran, G. AU - Murphy, G. AU - Fennelly, C. AU - O’Connor, R. PY - 2002 DA - 2002// TI - Identification of an IGF-1R kinase regulatory phosphatase using the fission yeast Schizosaccharomyces pombe and a GFP tagged IGF-1R in mammalian cells JO - Mol Pathol VL - 55 UR - https://doi.org/10.1136/mp.55.1.46 DO - 10.1136/mp.55.1.46 ID - Buckley2002 ER - TY - JOUR AU - Fan, G. AU - Lin, G. AU - Lucito, R. AU - Tonks, N. K. PY - 2013 DA - 2013// TI - Protein-tyrosine phosphatase 1B antagonized signaling by insulin-like growth factor-1 receptor and kinase BRK/PTK6 in ovarian cancer cells JO - J Biol Chem VL - 288 UR - https://doi.org/10.1074/jbc.M113.482737 DO - 10.1074/jbc.M113.482737 ID - Fan2013 ER - TY - STD TI - Perets R, Drapkin R. It’s totally tubular…riding the New wave of ovarian cancer research. Cancer Res. 2015. ID - ref51 ER - TY - JOUR AU - Elkin, S. R. AU - Bendris, N. AU - Reis, C. R. AU - Zhou, Y. AU - Xie, Y. AU - Huffman, K. E. PY - 2015 DA - 2015// TI - A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells JO - Cancer Res VL - 75 UR - https://doi.org/10.1158/0008-5472.CAN-15-0939 DO - 10.1158/0008-5472.CAN-15-0939 ID - Elkin2015 ER - TY - JOUR AU - Firth, S. M. AU - Baxter, R. C. PY - 2002 DA - 2002// TI - Cellular actions of the insulin-like growth factor binding proteins JO - Endocr Rev VL - 23 UR - https://doi.org/10.1210/er.2001-0033 DO - 10.1210/er.2001-0033 ID - Firth2002 ER - TY - JOUR AU - Oshima, A. AU - Nolan, C. M. AU - Kyle, J. W. AU - Grubb, J. H. AU - Sly, W. S. PY - 1988 DA - 1988// TI - The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells JO - J Biol Chem VL - 263 ID - Oshima1988 ER -