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Fig. 6 | BMC Systems Biology

Fig. 6

From: Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

Fig. 6

Sensitivity analysis demonstrated that pIGF1R was insensitive to changes in the IGF2R network. a Sensitivity of the integrated level of pIGF1R when individual rate parameters were changed. A positive value indicates an increase in the level of pIGF1R. b Sensitivity of the integrated level of pIGF1R when rate parameters are changed in combination with a 10-fold increase in the level of IGF2R. Parameters were altered such that both perturbations resulted in a decrease in the level of pIGF1R

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BMC Systems Biology

ISSN: 1752-0509

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