Fig. 5From: Differentiation resistance through altered retinoblastoma protein function in acute lymphoblastic leukemia: in silico modeling of the deregulations in the G1/S restriction point pathwaySemi-quantitative/qualitative criteria used for the calibration of the newly proposed model by optimization. The criteria are defined for (a) the phosphorylation status of the different pRb forms and (b) the levels of central model speciesBack to article page