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Fig. 7 | BMC Systems Biology

Fig. 7

From: Differentiation resistance through altered retinoblastoma protein function in acute lymphoblastic leukemia: in silico modeling of the deregulations in the G1/S restriction point pathway

Fig. 7

Random sampling and parameter scan result for pr bD4 and Modifier Time parameters. (a) By randomly sampling the two parameters, the model predicts a wide range of values for the G1/S Transition Time-point. (b) Parameter value samples taken during the random sampling procedure (c) Relationship between the observed G1/S Transition Time and pr bD4 values in random sampling parameter scan (d) Relationship between the observed G1/S Transition Time and pr bD4 values for constant value of Modifier Time (e) Relationship between G1/S Transition Time and Modifier Time for constant value of pr bD4 (f) Relationship between hypo-pRb detection time span and Modifier Time for constant value of pr bD4

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