Table 1 Mathematical definition of the reaction rate parameters of the newly introduced reactions
Relevant original reaction number in Fig. 4 | Newly introduced reaction number in Fig. 4 | Parameter name in original reactiona | New parameter definitionb |
|---|---|---|---|
r15 | r22 | k dE2F | \( {k}_{dE2{F}_{leuk}}=p{r}_{dE2F}*{k}_{dE2F} \) |
r1 | r5 | k bD4pRb | \( {k}_{bD4 pRbleuk}=p{r}_{bD4}*{k}_{bD4pRb} \) |
r9 | r17 | ″ | ″ |
r1 (reverse) | r5 (reverse) | k uD4pRb | \( {k}_{uD4 pRbleuk}=p{r}_{uD4}*{k}_{uD4pRb} \) |
r9 (reverse) | r17 (reverse) | ″ | ″ |
r2 | r6 | k upD4pRb | \( {k}_{uD4 pRbleuk}=p{r}_{uD4}*{k}_{uD4pRb} \) |
r10 | r18 | ″ | ″ |
r24 | r23 | k tpRbDephos | \( {k}_{tpRbDepho{s}_{leuk}}=p{r}_{tpRbDepho s}*{k}_{tpRbDepho s} \) |
r19 | r20 | ″ | ″ |
r16 | r21 | k uE2FpRb | \( {k}_{uE2 FpRb\_ leuk}=p{r}_{uE2F}*{k}_{uE2 FpRb} \) |
r11 | r21 (reverse) | k bE2FpRb | \( {k}_{bE2 FpRb\_ leuk}=p{r}_{bE2F}*{k}_{bE2 FpRb} \) |
r3 | r35 | k bE2pRb | \( {k}_{bE2pR{b}_{leuk}}=p{r}_{bE2A2A1}*{k}_{bE2pRb} \) |
r13 | r25 | ″ | ″ |
n.s. | r27 | k bA2pRb | \( {k}_{bA2pR{b}_{leuk}}=p{r}_{bE2A2A1}*{k}_{bA2pRb} \) |
n.s. | r29 | ″ | ″ |
n.s. | r31 | k bA1pRb | \( {k}_{bA1pR{b}_{leuk}}=p{r}_{bE2A2A1}*{k}_{bA1pRb} \) |
n.s. | r33 | ″ | ″ |
r3 (reverse) | r35 (reverse) | k uE2pRb | \( {k}_{uE2pR{b}_{leuk}}=p{r}_{uE2A2A1}*{k}_{uE2pRb} \) |
r13 (reverse) | r25 (reverse) | ″ | ″ |
n.s. | r27 (reverse) | k uA2pRb | \( {k}_{uA2pR{b}_{leuk}}=p{r}_{uE2A2A1}*{k}_{uA2pRb} \) |
n.s. | r29 (reverse) | ″ | ″ |
n.s. | r31 (reverse) | k uA1pRb | \( {k}_{uA1pR{b}_{leuk}}=p{r}_{uE2A2A1}*{k}_{uA1pRb} \) |
n.s. | r33 (reverse) | ″ | ″ |
r4 | r36 | k upE2pRb | \( {k}_{upE2pR{b}_{leuk}}=p{r}_{upE2A2A1}*{k}_{upE2pRb} \) |
r14 | r26 | ″ | ″ |
n.s. | r28 | k upA2pRb | \( {k}_{upA2pR{b}_{leuk}}=p{r}_{upE2A2A1}*{k}_{upA2pRb} \) |
n.s. | r30 | ″ | ″ |
n.s. | r32 | k upA1pRb | \( {k}_{upA1pR{b}_{leuk}}=p{r}_{upE2A2A1}*{k}_{upA1pRb} \) |
n.s. | r34 | ″ | ″ |