Fig. 2From: Molecular and cellular factors control signal transduction via switchable allosteric modulator proteins (SAMPs)Allosteric switching of a binding modulator. a Signal and response regulator bind to a modulator protein at distinct effector sites and influence each other allosterically. The cooperativity α quantifies the magnitude and sign of the cooperative effect between R and S. b Biochemical reaction scheme depicting the molecular complexes and reactions considered in the binding modulator model. M: modulator, R: response regulator, S: signalBack to article page