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Fig. 3 | BMC Systems Biology

Fig. 3

From: Molecular and cellular factors control signal transduction via switchable allosteric modulator proteins (SAMPs)

Fig. 3

Allosteric switching of an enzymatic modulator. a The signal and the activated response regulator bind at distinct effector sites to an enzymatic modulator. “A” denotes the active site. Enzymatic modulators have in principle two allosteric interaction modes: α B denotes the allosteric effect on ligand binding and α E that on the enzymatic reaction, respectively. b Biochemical reaction scheme depicting the molecular complexes and reactions considered in the enzymatic modulator model. M: modulator, R: inactive response regulator, R’: active response regulator, S: signal

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