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Fig. 5 | BMC Systems Biology

Fig. 5

From: Metabolic host responses to malarial infection during the intraerythrocytic developmental cycle

Fig. 5

Extracellular metabolite concentrations for the Plasmodium falciparum 3D7-infected human red blood cell culture. Time-dependent computed () and experimental () concentrations of extracellular metabolites in the medium of the infected red blood cell (RBC) culture during the intraerythrocytic development cycle (IDC). Increasing values indicate secretion, whereas decreasing values indicate uptake. Note that the initial concentration values at t = 0 h are set to the experimental values and the model predicts the concentration changes for t ≠ 0 h. Error bars represent 95 % confidence interval calculated as ± 1.96 σ/√ N, where the standard deviation σ was determined from the data and N represent the number of replicates. We used N = 3 experimental biological replicates and N = 20 simulation results, which were derived by adding 10 % Gaussian noise to the gene expression data (Additional file 1: Text S2)

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