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Fig. 1 | BMC Systems Biology

Fig. 1

From: Opening up the blackbox: an interpretable deep neural network-based classifier for cell-type specific enhancer predictions

Fig. 1

a A notional schematic showing the enhancer and the TSS (the promoter) relative to some of the True Positive Markers (TPMs)—DNase-I hypersensitivity site (DHS), p300 binding site, and transcription factor binding site (TFBS) (applicable to the H1 cell line). b Various forms of these TPMs overlap with the enhancer and the promoter sites. An overlap of the DHS with the TFBS can indicate an enhancer, while an enhancer is typically distal to the TSS. TPMs refer to DHS, p300, CBP, and TFBS

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