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Fig. 3 | BMC Systems Biology

Fig. 3

From: Classification of breast cancer patients using somatic mutation profiles and machine learning approaches

Fig. 3

Coefficient matrix (H). The coefficient matrix (H), 3 Ă— 358 in size, is used for assigning samples to clusters. The columns of the matrix represent patients and rows represent metagenes. We generated 3 metagenes that are used to cluster patients into 3 groups. The number of metagenes (rank of clustering) is determined by running the algorithm iteratively over a range of biologically reasonable parameters as explained in methods section

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