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Table 3 GSEA classification of 358 genes that have significantly higher mean mutation scores in cluster 3 compared to cluster 1

From: Classification of breast cancer patients using somatic mutation profiles and machine learning approaches

GSEA gene families

Cytokines/growth factors

Transcription factors

Homeodomain proteins

Cell differentiation markers

Protein kinases

Translocated cancer genes

Oncogenes

Tumor suppressors

Tumor suppressors

0

1

0

0

0

1

0

4

Oncogenes

0

3

0

0

0

11

12

 

Translocated cancer genes

0

4

0

0

0

12

  

Protein kinases

0

0

0

1

16

   

Cell differentiation markers

0

0

0

4

    

Homeodomain proteins

0

3

3

     

Transcription factors

0

25

      

Cytokines and growth factors

3

       
  1. Note that some of the genes in our gene list are not found in any GSEA (Gene Set Enrichment Analysis) gene family