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Table 1 Three known AD-associated metabolites ranked highly

From: Towards understanding brain-gut-microbiome connections in Alzheimer’s disease

Metabolite AD types Enrichment P value
Mannitol AD cognitive decline 353.4 % 2.91E-28
  AD biomarkers 201.5 % 1.16E-19
  AD (late onset) 54.8 % 6.23E-13
  AD, susceptibility to 8957.1 % 2.34E-32
Succinic acid AD cognitive decline 459.5 % 2.37E-31
  AD, susceptibility to 1662.5 % 1.25E-30
3,4-dihydroxybenzeneacetic acid (DOPAC) AD biomarkers 262.7 % 9.40E-26
  AD (age of onset) 47.2 % 1.75E-8
  AD, susceptibility to 1602.5 % 1.49E-30