Table 1 Three known AD-associated metabolites ranked highly
From: Towards understanding brain-gut-microbiome connections in Alzheimer’s disease
Metabolite | AD types | Enrichment | P value |
|---|---|---|---|
Mannitol | AD cognitive decline | 353.4 % | 2.91E-28 |
AD biomarkers | 201.5 % | 1.16E-19 | |
AD (late onset) | 54.8 % | 6.23E-13 | |
AD, susceptibility to | 8957.1 % | 2.34E-32 | |
Succinic acid | AD cognitive decline | 459.5 % | 2.37E-31 |
AD, susceptibility to | 1662.5 % | 1.25E-30 | |
3,4-dihydroxybenzeneacetic acid (DOPAC) | AD biomarkers | 262.7 % | 9.40E-26 |
AD (age of onset) | 47.2 % | 1.75E-8 | |
AD, susceptibility to | 1602.5 % | 1.49E-30 |