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Table 2 Top 15 synergistic drug pairs predicted by the co-gene/GS score in the DREAM dataset

From: A simple gene set-based method accurately predicts the synergy of drug pairs

Drug pair Co-gene/GS score Predicted rank Gold-standard rank
Camptothecin & Mitomycin C 0.084 1 5
Camptothecin & Doxorubicin 0.036 2 16
H-7 & Mitomycin C 0.032 3 2
Methotrexate & Mitomycin C 0.030 4 28
Doxorubicin & Mitomycin C 0.027 5 4
Cycloheximide & H-7 0.027 6 9
Camptothecin & Etoposide 0.025 7 15
H-7 & Trichostatin A 0.019 8 19
H-7 & Rapamycin 0.017 9 27
Camptothecin & H-7 0.015 10 10
Etoposide & Mitomycin C 0.015 11 3
H-7 & Vincristine 0.012 12 43
H-7 & Monastrol 0.012 13 14
Cycloheximide & Methotrexate 0.011 14 64
Doxorubicin & H-7 0.011 15 1