Table 2 Top 15 synergistic drug pairs predicted by the co-gene/GS score in the DREAM dataset
From: A simple gene set-based method accurately predicts the synergy of drug pairs
Drug pair | Co-gene/GS score | Predicted rank | Gold-standard rank |
|---|---|---|---|
Camptothecin & Mitomycin C | 0.084 | 1 | 5 |
Camptothecin & Doxorubicin | 0.036 | 2 | 16 |
H-7 & Mitomycin C | 0.032 | 3 | 2 |
Methotrexate & Mitomycin C | 0.030 | 4 | 28 |
Doxorubicin & Mitomycin C | 0.027 | 5 | 4 |
Cycloheximide & H-7 | 0.027 | 6 | 9 |
Camptothecin & Etoposide | 0.025 | 7 | 15 |
H-7 & Trichostatin A | 0.019 | 8 | 19 |
H-7 & Rapamycin | 0.017 | 9 | 27 |
Camptothecin & H-7 | 0.015 | 10 | 10 |
Etoposide & Mitomycin C | 0.015 | 11 | 3 |
H-7 & Vincristine | 0.012 | 12 | 43 |
H-7 & Monastrol | 0.012 | 13 | 14 |
Cycloheximide & Methotrexate | 0.011 | 14 | 64 |
Doxorubicin & H-7 | 0.011 | 15 | 1 |