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Table 4 Commonly enriched gene sets of doxorubicin and H-7 in the DREAM dataset

From: A simple gene set-based method accurately predicts the synergy of drug pairs

Gene set MSigDB category
NEWMAN_ERCC6_TARGETS_DN Chemical and genetic perturbations
LEE_NEURAL_CREST_STEM_CELL_DN Chemical and genetic perturbations
ODONNELL_METASTASIS_UP Chemical and genetic perturbations
CERVERA_SDHB_TARGETS_2 Chemical and genetic perturbations
OSADA_ASCL1_TARGETS_UP Chemical and genetic perturbations
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP Chemical and genetic perturbations
HINATA_NFKB_TARGETS_KERATINOCYTE_DN Chemical and genetic perturbations
TAVAZOIE_METASTASIS Chemical and genetic perturbations
VALK_AML_CLUSTER_7 Chemical and genetic perturbations
MIKKELSEN_NPC_ICP_WITH_H3K27ME3 Chemical and genetic perturbations
HOELZEL_NF1_TARGETS_UP Chemical and genetic perturbations
PTEN_DN.V2_UP Oncogenic signatures
KRAS.DF.V1_DN Oncogenic signatures
Response to wounding Gene ontology terms