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Fig. 1 | BMC Systems Biology

Fig. 1

From: A novel integrated gene coexpression analysis approach reveals a prognostic three-transcription-factor signature for glioma molecular subtypes

Fig. 1

Clustering heat maps and survival analysis results with 88 seed genes in four data sets. The numbers of clusters (k) were determined by NMF based on the expression signatures of 88 potential glioma regulation related genes. Heat maps of 88 genes in glioma samples are shown on the left. a-d are respectively GSE16011, Rembrandt data set, Tiantan data set, and TCGA mRNA-seq data set. Kaplan-Meier survival curves of the overall survival for the patients from each molecular subtype are shown on the right. P-values of the survival curves were calculated by using log-rank tests. The same colour codes were used in the heat maps and the Kaplan-Meier survival curves in all datasets

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