Skip to main content


Fig. 3 | BMC Systems Biology

Fig. 3

From: Stochastic modeling suggests that noise reduces differentiation efficiency by inducing a heterogeneous drug response in glioma differentiation therapy

Fig. 3

Heterogeneous response of cyclin D1 and GFAP in glioma cells simulated using the ANM model. The simulated cells were subjected to continuous stimulation with CT (10 ng/ml) for 48 h. The stochastic evolution of cyclin D1 and GFAP activity was simulated with different noise intensities (0.1 % (a, b), 1 % (c, d), 5 % (e, f) and 10 % (g, h), respectively) of signal variation

Back to article page