Fig. 2

Overview of the tool’s user interface: ① At top there are adjustable parameter settings for CPM computation and ③ buttons for initializing and computing the lattice sites. ② The left side shows the initialization output as rendered graph with grey nodes representing parts of ECM, while colored nodes representing cellular bricks corresponding either to light blue colored (normal/healthy) or dark red colored (tumor/mutated) cells. The table below shows information about the initialized cell data. ⑤ The right side shows the output for the last computation step, while the table below contains computed cell data. ④ A toggle buttons controls the ⑥ lightbox in the middle that provides line chart visualization and export