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Fig. 4 | BMC Systems Biology

Fig. 4

From: Properties of Boolean dynamics by node classification using feedback loops in a network

Fig. 4

Changes in proportions of functionally important genes over the threshold value of the perturbation-sustainable probability. Given a threshold value β, the y-axis values indicate the proportions of essential genes, disease genes, and drug targets over the set of candidate genes whose perturbation-sustainable probability is larger than or equal to β. The larger the value of β, the smaller the number of candidate genes is. a Results of essential genes, disease genes, and drug targets in the KEGG network. For a reliable comparison, the maximal β was set to 0.0179 which generates 121 candidate genes. b Results of essential genes, disease genes, and drug targets in the WANG network. The maximal β was set to 1.0000, which results in 546 candidate genes

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