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Fig. 3 | BMC Systems Biology

Fig. 3

From: IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8+ T cell-APC: a multiscale modeling study

Fig. 3

CD8+ T cell dynamics in various antigenic stimulation environments in silico. a Only the control population (stimulated with strong antigens) and the population submitted to a weak antigenic stimulation together with additional IL-2 supplement are able to proliferate (mean ± SD; n = 10 simulations). b CD8+ T cell dynamics in a weak antigenic condition with graded doses of IL-2 supplement (0.3–10 ng/ml) (mean ± SD; n = 10 simulations). c IL-2•IL-2R expression (mean; n = 10 simulations) and d the activated cells fold-increases (mean ± SD; n = 10 simulations) under the conditions of weak antigenic stimulation with or without 10 ng/ml IL-2

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BMC Systems Biology

ISSN: 1752-0509

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