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Fig. 1 | BMC Systems Biology

Fig. 1

From: Drug combinatorics and side effect estimation on the signed human drug-target network

Fig. 1

Drug and target connectivity analysis on the human network. Panel a The main plot shows the number of human targets associated to each drug. In blue the total number of targets is shown, while in red and green are respectively the number of targets for which the mode of action can be classified as positive (red) and negative (green). The inset shows the same quantities but only for the 50 drugs having the highest total number of targets in DrugBank. Panel b The main plot shows the number of drugs associated to each human target. In violet the total number of drugs is shown, while in red and cyan are respectively the number of drugs with positive (red) and negative (cyan) modes of action. The inset shows the same quantities but only for the 100 targets having the highest total number of drugs in DrugBank

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