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Fig. 3 | BMC Systems Biology

Fig. 3

From: The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus

Fig. 3

Validation of network predictions. Network neighborhoods for each of the target gene deletions tested were assessed for their expression difference from the rest of the network using a Student’s t test. Neighborhoods are defined in terms of the WGCNA module that contains the target gene (blue bars) or the first-order network of the target gene from the CLR-inferred network (red bars). All comparisons shown have p values less than 0.001. Standard error is shown for each data point as error bars. Negative mean expression indicates that deletion of the target gene is reducing the expression of its neighborhood compared to response in a wild type mouse

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