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Fig. 4 | BMC Systems Biology

Fig. 4

From: The potential for non-adaptive origins of evolutionary innovations in central carbon metabolism

Fig. 4

Potential for preadaptation depends on biochemical similarity between carbon sources. a The histogram shows the fraction of metabolisms viable on glucose as carbon source C that are also viable on each of the nine other carbon sources C new (x-axis). b As in (a), but broken down by metabolism size, and fractions of viable metabolisms are represented by different shades of grey (see legend). c Fraction of metabolisms viable on carbon source C (x-axis), which are also viable on carbon source C new (y-axis), (coded by shade of grey, see legend). d Dendrogram of carbon sources clustered based on their pairwise preadaptation propensity. We used UPGMA method (unweighted pair group method with arithmetic means) for clustering carbon sources

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