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Table 1 Contingency and contingency tests with HLT baseline

From: A method for automated pathogenic content estimation with application to rheumatoid arthritis

a. Contingency ∑|Δg|

Eubiotic frequency

Dysbiotic frequency

NORA-HLT

314

7977

UCRA-HLT

0

16

MTX-HLT

1965

0

Prednisone-HLT

266

102

b. Contingency test p-values

NORA

UCRA

MTX

Prednisone

NORA

 

0.54

1

1

UCRA

1

 

1

1

MTX

0

3.95E-40

 

1

Prednisone

1.24E-251

2.99E-09

1

 
  1. a. Condition-impact contingency table with cumulated frequencies accounted for harmless and pathogenic impacts (column) under the compared conditions (row). ∑|Δg| is the result of an increase of harmless bacteria abundances plus decrease (absolute value) of harmful bacteria abundances for eubiotic microbiomes and viceversa for dysbiotic. b. Contingency test assessing the hypothesis that the condition in the row is more associated to a more harmless composition than the condition in the column. One-sided Fisher’s exact test, p < 0.05, in bold)