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Fig. 13 | BMC Systems Biology

Fig. 13

From: DGCA: A comprehensive R package for Differential Gene Correlation Analysis

Fig. 13

The differential correlation module most enriched in gene pairs that gain in correlation in ER+ breast cancer. This module of genes was identified using MEGENA and chosen for downstream analysis because it was most enriched for the gene pairs with positive correlations in ER+ breast cancer but no significant correlation in triple negative (TN) breast cancer. Node size and gene symbol text size are proportional to the number of connections for each gene. Edges are colored according to the differential correlation class (see Legend), while edge weight is proportional to the absolute value of the z-score for the difference of correlation between ER+ and TN breast cancer samples. This plot was made using Cytoscape (version 3.2.1)

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