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Fig. 6 | BMC Systems Biology

Fig. 6

From: DGCA: A comprehensive R package for Differential Gene Correlation Analysis

Fig. 6

Expression correlations of five genes with TP53 in samples with and without p53 mutations. Expression values for genes from breast cancer samples without p53 mutation, or p53 wildtype (WT; red, n = 590), compared to samples with non-silent p53 coding mutations (blue, n = 254). For each gene pair, the expression of TP53 is on the x-axis, while the expression of GNB2L1 a, RPS12 b, CDKN1A c, TSC22D1 d, and DGKA e are on the y-axis. For visualization purposes, a linear model was fit to the data in each comparison, with the grey lines representing 95% confidence intervals. This visualization was made using a DGCA wrapper function to the ggplot2 R package

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