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Table 4 Top aging markers with their betweennesses in the PPI network

From: Integrative analysis of methylation and transcriptional profiles to predict aging and construct aging specific cross-tissue networks

Gene

Betweenness

P-value

TP53

1023

0.016*

HSP90AA1

665

0.009*

SRC

363

0.086

STAT3

263

0*

BMP2

254

0*

AKT1

243

0.759

CD8A

235

0*

EP300

229

0*

HSPA4

221

0*

IL6

207

0.018*

  1. *: p-value < 0.05, significant