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Fig. 4 | BMC Systems Biology

Fig. 4

From: Subtype-specific CpG island shore methylation and mutation patterns in 30 breast cancer cell lines

Fig. 4

Differentially methylated and experimentally validated promotor TFBS in CpGI shore region having negative correlation with downstream gene expression. The differential methylation of the overlapped region among breast cancer cell subtypes was tested by Kruskal Wallis test with FDR < 0.1, and the methylation status was inversely correlated with downstream gene expression (Spearman rank correlation < -0.5). X-axis shows genomic location of each genes and Y-axis represents DNA methylation level measured by MBDcap sequencing

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