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Table 3 AUC of the functional similarity measures for three GOs using BMA in the PPI task on yeast dataset (IEA+ and IEA-)

From: An improved method for functional similarity analysis of genes based on Gene Ontology

Methods

BP_IEA+

BP_IEA-

CC_IEA+

CC_IEA-

MF_IEA+

MF_IEA-

simUI

0.8528

0.8381

0.8301

0.8349

0.7901

0.7771

Teng

0.8622

0.8493

0.8319

0.8424

0.7921

0.7705

simGIC

0.8688

0.8560

0.8359

0.8427

0.8128

0.7923

Wang

0.8693

0.8593

0.8472

0.8533

0.8198

0.8224

Resnik

0.8864

0.8681

0.8598

0.8446

0.8412

0.8086

JC

0.8497

0.8645

0.8074

0.8359

0.7872

0.8128

Lin

0.8768

0.8680

0.8475

0.8511

0.8226

0.8047

ResnikGrasm

0.8696

0.8581

0.8332

0.8228

0.7740

0.7719

WangWV

0.8581

0.8622

0.8401

0.8431

0.8118

0.8218

simRel

0.8816

0.8722

0.8688

0.8600

0.8208

0.8082

WIS

0.8907

0.8792

0.8517

0.8628

0.8367

0.8232

  1. The best results are in bold