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Table 8 Comparisons of IC computational models

From: An improved method for functional similarity analysis of genes based on Gene Ontology

Models

Whether the information of t affects the result

Corpus

Depth(t)

Descendant(t)

Leaves(t)

Ancestors(t)

Sanchez

No

No

No

Yes

Yes

Seco

No

No

Yes

No

No

Teng

No

Yes

Yes

No

No

WIS

No

Yes

Yes

No

Yes

  1. Each model may employ different information of term t to measure its IC. We list out five types of information and discuss the characteristics of these four models above. “No” denotes that the factor has no effect on the model and vice versa. The corresponding explanation for each factor has been introduced in previous chapter