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Table 3 Prediction on archived GOA files using TO (see Eq. (5))

From: Interspecies gene function prediction using semantic similarity

  

MicroAvgF1

MacroAvgF1

1-RankLoss

Fmax

RAccuracy

CC

H →H

0.8374

0.7212

0.8968

0.8729

0.1773

 

M →H

0.8351

0.7241

0.8969

0.8743

0.1762

 

M+H →H

0.8586

0.7641

0.9771

0.8751

0.2845

 

D →H

0.8351

0.7322

0.8941

0.8693

0.1662

 

D+H →H

0.8512

0.7476

0.9422

0.8654

0.2469

 

A →H

0.8317

0.6982

0.8832

0.8860

0.1488

 

A+H →H

0.8366

0.7223

0.8962

0.8726

0.1732

 

M →M

0.7765

0.6075

0.8826

0.8526

0.2122

 

H →M

0.7805

0.6130

0.8836

0.8295

0.2166

 

H+M →M

0.8132

0.6547

0.9597

0.8665

0.3418

 

D →M

0.7726

0.6142

0.8659

0.8320

0.2092

 

D+M →M

0.7993

0.6357

0.9252

0.8384

0.2928

 

A →M

0.7758

0.6278

0.8700

0.8324

0.2105

 

A+M →M

0.7770

0.6088

0.8807

0.8447

0.2142

MF

H →H

0.8569

0.8228

0.9293

0.8952

0.1687

 

M →H

0.8542

0.8213

0.9262

0.8941

0.1527

 

M+H →H

0.8711

0.8382

0.9763

0.9064

0.2510

 

D →H

0.8524

0.8348

0.9413

0.8717

0.1426

 

D+H →H

0.8606

0.8349

0.9588

0.8979

0.1901

 

A →H

0.8456

0.8225

0.9124

0.8941

0.1026

 

A+H →H

0.8535

0.8181

0.9260

0.8933

0.1489

 

M →M

0.7756

0.6946

0.8985

0.8692

0.1697

 

H →M

0.7804

0.6957

0.9096

0.8569

0.1677

 

H+M →M

0.7851

0.7104

0.9374

0.8806

0.2051

 

D →M

0.7695

0.6811

0.8963

0.8602

0.1538

 

D+M →M

0.7851

0.7082

0.9356

0.8731

0.2051

 

A →M

0.7635

0.6941

0.8816

0.8588

0.1249

 

A+M →M

0.7752

0.6840

0.8993

0.8616

0.1683

BP

H →H

0.8460

0.8019

0.9605

0.8729

0.2472

 

M →H

0.8428

0.7998

0.9586

0.7818

0.2316

 

M+H →H

0.8500

0.8071

0.9745

0.8751

0.2664

 

D →H

0.8385

0.8036

0.9605

0.7901

0.2101

 

D+H →H

0.8443

0.8016

0.9613

0.7877

0.2387

 

A →H

0.8314

0.7943

0.9333

0.7591

0.1755

 

A+H →H

0.8389

0.7933

0.9520

0.7813

0.2120

 

M →M

0.7960

0.7101

0.9519

0.7813

0.2405

 

H →M

0.7980

0.7073

0.9532

0.7767

0.2481

 

H+M →M

0.8024

0.7163

0.9677

0.8244

0.2643

 

D →M

0.7886

0.7137

0.9508

0.7756

0.2129

 

D+M →M

0.7832

0.7059

0.9410

0.7765

0.2318

 

A →M

0.7795

0.7020

0.9158

0.7373

0.1791

 

A+M →M

0.7723

0.6923

0.9326

0.7716

0.2106

  1. H →H directly uses GO annotations of Human to predict annotations of Human genes. M →H only employs annotations of genes from Mouse to predict annotations of Human genes. M+H →H uses GO annotations of genes from Mouse and Human to predict annotations of Human genes. D+H →H uses annotations of genes from Danio rerio and Human to predict annotations of Human genes. A+H →H uses annotations of genes from Arabidopsis thaliana and Human to predict annotations of Human genes. M →M, H+M →M, D+M →M and A+M →M follow the similar protocol, but predict annotations of Mouse genes. The data in boldface is the statistically significant best among these comparing methods for a particular target species, and the significance is checked by paired t-test at 95% confidence intervals
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BMC Systems Biology

ISSN: 1752-0509

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