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Fig. 1 | BMC Systems Biology

Fig. 1

From: Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

Fig. 1

Differentially expressed genes in 22q11.2 SZ neurons and their enriched functions. a Heat map showing relative expression of 782 genes that exhibited significant change between control and SZ at p-value < 0.05 (503 increased in SZ; 279 decreased). b Bar plot presenting batch-corrected expression values of 22q11.2 genes in control and SZ samples. Three genes flanking the deleted region at either side were also included. Asterisks (*) indicate significant differential expression at the genome-wide level (FDR < 0.05). c Enriched GO terms of the DEGs as determined by the software David. d Enriched pathways for the DEGs as determined by the software Toppgene

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BMC Systems Biology

ISSN: 1752-0509

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