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Fig. 1 | BMC Systems Biology

Fig. 1

From: Unearthing the transition rates between photoreceptor conformers

Fig. 1

An overview of the method. To obtain photoreceptor photoconversion cross-sections and quantum yields, four computational steps are required once the appropriate data has been obtained (Box 1). First, the parameters for thermal reversion - the rate of reversion and the percentage of the photoreceptor population that experiences this rate - need to be found (Box 2). Given these values, an analytical method is then used to find the search spaces for our optimisation algorithm (Box 3). Once the parameters and search spaces have been obtained, the values can be found using our optimisation algorithm (Box 4). Finally, the optimal values can be verified by comparing simulations to the rest of our available data (Box 5)

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