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Fig. 1 | BMC Systems Biology

Fig. 1

From: The quality of metabolic pathway resources depends on initial enzymatic function assignments: a case for maize

Fig. 1

Overview of the pipelines used to create CornCyc 4.0 and MaizeCyc 2.2. Green represents common components, and orange and blue CornCyc- and MaizeCyc-specific components respectively. CornCyc and MaizeCyc were both based on the B73 RefGen_v2 gene model. They mainly differed in different functional annotation prediction methods incorporated into their respective pipelines. Both databases used Pathway Tools and MetaCyc for their reaction and pathway inference. Since both databases were created at different times, they used different versions of MetaCyc. Finally, manual curation has been applied to both databases. In order to account for differences at the pathway and reaction inference steps as well as at the manual curation step, we propagated updates from the same version of MetaCyc to both databases and allowed the propagation utility to remove manually curated data

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