Fig. 4From: Receptor-guided 3D-QSAR studies, molecular dynamics simulation and free energy calculations of Btk kinase inhibitorsChange evaluated in terms of distance between crucial active site residues and compound 26. a Distance between oxygen atom of Thr474 and H17 of compound 26; b Distance between Oxygen atom of Glu475 and H18 of compound 26; c Distance between Oxygen atom of Met477 and N2 of compound 26; d Distance between hydrogen atom of Asp539 and O16 of compound 26 Back to article page