Table 7 Results of independent testing of our method on 6 datasets with different P:N ratios of positive to negative instances
From: Predicting protein-binding regions in RNA using nucleotide profiles and compositions
P:N | Sensitivity | Specificity | Accuracy | PPV | NPV | MCC |
|---|---|---|---|---|---|---|
1:1 | 72.50% | 91.90% | 82.20% | 89.95% | 76.97% | 0.656 |
1:2 | 72.40% | 91.80% | 85.33% | 81.53% | 86.93% | 0.663 |
1:4 | 74.10% | 91.10% | 87.70% | 67.55% | 83.36% | 0.630 |
1:6 | 77.00% | 90.26% | 88.37% | 56.87% | 95.92% | 0.596 |
1:8 | 77.80% | 89.68% | 88.36% | 48.53% | 97.00% | 0.554 |
1:10 | 79.10% | 89.70% | 88.73% | 43.44% | 97.72% | 0.532 |