(a)
|
Data
|
PINTnet
|
OGB
|
 |
Evidence-supported
a
|
All
b
|
Evidence-supported
a
|
All
b
|
Dataset1 | 9 | 92 | 1 | 109 |
Dataset2 | 15 | 122 | 2 | 268 |
Dataset3 | 1 | 149 | 1 | 291 |
(b)
|
Data
|
PINTnet
|
OGB
|
 |
Evidence-supported
c
|
All
d
|
Evidence-supported
c
|
All
d
|
Dataset1 | 9.500 | 3.067 | 3.800 | 2.344 |
Dataset2 | 9.700 | 3.697 | 4.000 | 3.829 |
Dataset3 | 5.000 | 2.922 | 6.000 | 4.376 |
(c)
|
Data
|
Found
e
|
All
f
| Â |
 |
PINTnet
|
OGB
| Â | Â |
Dataset1 | 8 | 6 | 8 | Â |
Dataset2 | 10 | 9 | 10 | Â |
Dataset3 | 6 | 4 | 6 | Â |
- (a) The number of edges between the pathways in the pathway interaction network. The first column of each approach is the number of edges between the evidence-supported pathways. The second column of each approach is the number of edges between all pathways in the network
- (b) The average degree of the pathways in the pathway interaction network. The first column of each approach is the average degree of the evidence-supported pathways. The second column of each approach is that of all pathways in the network
- (c) The number of evidence-supported pathway found in the network. The first column is the number of evidence-supported pathways that are found in the pathway interaction network constructed using our method. The second column is the number of evidence-supported pathways that are found in the pathway interaction network constructed using OGB. The third column is the number of all evidence-supported pathways
-
aThe number of edges connecting the evidence-supported pathways
-
bThe total number of edges in the pathway interaction network
-
cThe average degree of the evidence-supported pathways
-
dThe average degree of all pathways in the pathway interaction network
-
eThe number of evidence-supported pathways in the pathway interaction networks constructed using both approaches
-
fThe total number of evidence-supported pathways